I’m not an industry analyst. I’m sure there can be papers written about why some games stay with us (Dungeons & Dragons, Call of Cthulhu) and why others get their release and vanish into the mists of time (Arduin, Empires of the Petal Throne, etc.). There will always be people who regard a long-dead game fondly and insist it’s still relevant, even if the majority of tabletop gamers have never heard of it or seen it played.
I think games that can handle both laser-focused games and large, open-ended epics with classic themes probably have greater staying power than games that seem focused on a trope or a narrow theme (like Paranoia; unless you play it in a more serious, less deadly style, it’s going to wear thin about as fast as you go through clones). That’s just my personal experience, though.